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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP1
All Species:
23.64
Human Site:
Y169
Identified Species:
57.78
UniProt:
P28562
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28562
NP_004408.1
367
39298
Y169
S
S
C
S
T
P
L
Y
D
Q
G
G
P
V
E
Chimpanzee
Pan troglodytes
XP_520046
394
42978
H191
S
S
C
G
T
P
L
H
D
Q
G
G
P
V
E
Rhesus Macaque
Macaca mulatta
XP_001096004
367
39437
Y169
S
S
C
S
T
P
L
Y
D
Q
G
G
P
V
E
Dog
Lupus familis
XP_546235
367
39453
Y169
S
S
C
S
T
P
L
Y
D
Q
G
G
P
V
E
Cat
Felis silvestris
Mouse
Mus musculus
P28563
367
39351
Y169
S
S
C
S
T
P
L
Y
D
Q
G
G
P
V
E
Rat
Rattus norvegicus
Q64623
367
39523
Y169
S
S
C
S
T
P
L
Y
D
Q
G
G
P
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PW71
375
41034
H172
S
S
C
G
T
P
L
H
D
Q
G
G
P
V
E
Frog
Xenopus laevis
NP_001080570
369
40246
Y171
T
P
C
G
T
P
L
Y
D
Q
G
G
P
V
E
Zebra Danio
Brachydanio rerio
NP_998232
360
39513
T165
T
A
D
S
S
C
N
T
C
T
T
P
L
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10038
657
70984
P171
S
Q
P
C
L
S
Q
P
T
G
D
G
I
T
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.4
99.1
98
N.A.
96.4
97
N.A.
N.A.
64.5
78.5
71.3
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
100
72.8
99.4
98.6
N.A.
98
98
N.A.
N.A.
76.2
88
82.5
N.A.
N.A.
N.A.
32.4
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
86.6
80
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
33.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
80
10
0
10
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
80
0
10
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
30
0
0
0
0
0
10
80
90
0
0
0
% G
% His:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
80
0
0
0
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
0
0
80
0
10
0
0
0
10
80
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
80
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
80
70
0
60
10
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
20
0
0
0
80
0
0
10
10
10
10
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _